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Search Results for " atm and rad3 related "

14

Compounds

Cat No. Product Name Synonyms Targets
T5175 Azd1390 ATM/ATR
AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes.
T3338 Ceralasertib AZD6738 ATM/ATR
Ceralasertib (AZD6738) is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM.
T1958 AZ20 ATM/ATR , mTOR
AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.
T4443 AZ32 ATM/ATR
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.
T6770 AZD0156 Apoptosis , ATM/ATR
AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.
T2685 KU-55933 ATM Kinase Inhibitor ATM/ATR , DNA-PK , PI3K , mTOR , Autophagy
KU-55933 (ATM Kinase Inhibitor) is a potent and specific ATM inhibitor.
T1821 CGK733 CGK 733 ATM/ATR
CGK733 (CGK 733) is a potent and selective inhibitor of ATM/ATR.
T6261 CP-466722 CP 466722,CP466722 ATM/ATR
CP-466722, an effective and reversible ATM inhibitor, does not inhibit ATR and PI3K or PIKK family members in cells.
T2084 ETP-46464 ATM/ATR , DNA-PK , PI3K , mTOR
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
T3032 VE-821 ATR Inhibitor IV ATM/ATR
VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).
TN1673 Garcinone C ATM/ATR , CDK , STAT , AChR , Antifection
Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effe...
T6612 NU6027 ATM/ATR , DNA-PK , CDK
NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-aminopurine-based inhibitors.
T7318 Elimusertib BAY-1895344 ATM/ATR
Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target...
T7122 AZD-7648 DNA-PK
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.
TargetMol